Google has launched what it calls a world-first smartphone experience in central London as the search giant looks to cement its presence on the high street.The Google Shop will see customers able to experience devices ranging from Nexus smartphones and tablets, Chromebooks, Chromecasts and Android Wear smartwatches as well as experience some of Googles other online services.The store allows customers to experience an interactive Google Maps experience on a large curved display, as well as creating their own Google Doodles on an interactive wall.The first Google Shop will be located in the Currys/PC World store on Tottenham Court Road with two similar installations planned for later this year. The shop is seen as a step-up from the current partnerships the company has in place with retailers in the UK where it has a limited presence within over 400 stores across the country.Retail storesSpeaking to IBTimes UK at the launch Google UKs marketing director James Elias said this was the biggest and boldest evolution of [Googles] store-in-store strategy to date but when asked if this was just a gateway to building its own standalone stores, Elias said the company had no plans along those lines.Apple announced earlier this week, on 9 March, that the company now had over 450 retail stores worldwide with aggressive plans to expand that number in China in particular. The company saw some 120 million people pass through the doors of its stores in just three months to the end of December, giving some idea of the revenue generating potential of the stores.Google is a very different business and while it has some hardware in the form of Nexus devices, these are built in partnership with the likes of HTC and Motorola and therefore the potential revenue gain for the search giant is not as instantly obvious as for Apple.Elias said that while the company was hoping the new Google Shop would help drive some revenue, it was as much about the experience, adding that the store wants to become part of the community with classes about how to stay safe online being held at the store in the future. Close
After giving your details, click on ‘Get Result’You can download your results and take a printout of it (Representational Image)PixabayThe Tamil Nadu Directorate of Government Examination, TNDGE, has released the dates for the exam results. According to the notification, Tamil Nadu SSLC or class 10 results will be announced on April 29.The results are expected to come out in the morning since the class 12 results were also declared at 9.30 am on April 19. The class 11 examination results will be announced on May 8.Over 10 lakh students appeared for the class 10 examinations which were held between March 14 and March 29. Students are expected to have a minimum of 35 per cent in each subject to pass the examinations and go to the next class.You can check your results by following the steps given belowGo to the link tnresults.nic.in, dge1.tn.nic.in or dge2.tn.nic.in.Click on the option for the Tamil Nadu 10th Result 2019’ the link is not activated now. It will be valid after the results are declaredEnter your registration number and date of birth
A minor girl was killed after she was suspected to be raped by unidentified persons at Gachhabari village in Tangail’s Madhupur upazila on Friday, reports UNB.The deceased was identified as Liza Akhter, daughter of Mizanur Rahman of the village.Locals said Liza had been missing since Friday afternoon after she went to take bath in a nearby river.Later in the night, locals spotted the body in the bush beside her house and informed police.On the next morning, police recovered the body and sent it to Tangail General Hospital for autopsy.Liza could have been raped before being murdered, said Shafiqul Islam, officer-in-charge of Madhupur police station.A murder case was filed with the police station in this regard, said the OC.
This file photo taken on 4 April 2017 shows an unconscious Syrian child receiving treatment at a hospital in Khan Sheikhun, a rebel-held town in the northwestern Syrian Idlib province, following a suspected toxic gas attack. AFPUnited Nations investigators on Thursday blamed a sarin gas massacre on Bashar al-Assad’s regime, as the United States renewed its warning that he has no role in Syria’s future.The expert panel’s report and tough remarks by US secretary of state Rex Tillerson overshadowed the announcement that UN-sponsored peace talks will resume next month.More than 87 people died on 4 April this year when sarin gas projectiles were fired into Khan Sheikhun, a rebel-held town in the Idlib province of northwestern Syria.Images of dead and dying victims, including young children, in the aftermath of the attack provoked global outrage and a US cruise missile strike on a regime air base.Syria and its ally Russia had suggested that a rebel weapon may have detonated on the ground but the UN panel confirmed Western intelligence reports that blamed the regime.“The panel is confident that the Syrian Arab Republic is responsible for the release of sarin at Khan Sheikhun on 4 April 2017,” the report, seen by AFP, says.The report will increase pressure on Assad’s regime just as Washington, in the wake of battlefield victories against the Islamic State group, renews calls for him to step down.Secretary of State Rex Tillerson’s comments to reporters came during a visit to Geneva in which he met UN envoy Staffan de Mistura, who is trying to convene a new round of peace talks next month.The secretary said US policy has not changed, but his remarks represented tougher language from an administration that had previously said Assad’s fate is not a priority.“We do not believe there is a future for the Assad regime, the Assad family,” Tillerson said.“I think I’ve said it on a number of occasions. The reign of the Assad family is coming to an end, and the only issue is how should that be brought about.”Russia, which is running a parallel peace process with Iran and Turkey in a series of talks in the Kazakh capital Astana, reacted coolly to Tillerson’s remarks.“I think we should not pre-empt any future for anybody,” said Moscow’s UN ambassador Vassily Nebenzia, who on Tuesday had vetoed a US attempt to extend the gas attack probe.British Foreign Secretary Boris Johnson said the UN panel’s report had reached a “clear conclusion” and urged the “international community to unite to hold Assad’s regime accountable.”“I call on Russia to stop covering up for its abhorrent ally and keep its own commitment to ensure that chemical weapons are never used again,” he said.Civil warDe Mistura hopes to convene an eighth round of Syrian peace talks between Assad’s regime and an opposition coalition in Geneva from 28 November.These will be focused on drafting a new constitution and holding UN-supervised elections in a country devastated by several overlapping bloody civil conflicts.Assad’s regime has been saved by Russian and Iranian military intervention and he insists that he will not stand down in the face of what he regards as “terrorist” rebels.But Western capitals, the opposition and many of Syria’s Arab neighbors hold Assad’s forces responsible for the bulk of the 330,000 people who have died in the conflict.In addition to chemical weapons attacks against his own people, his government is accused of overseeing the large-scale torture and murder of civilian detainees.The previous US administration often said that Assad’s days were numbered, but then president Barack Obama decided not to use force to punish his chemical weapons attacks.His successor, President Donald Trump, did order one missile strike on a Syrian air base in response to a chemical attack.But US policy has otherwise focused solely on the defeat of the Islamic State jihadist group, driving it out of its last bastions in eastern Syria’s Euphrates valley.Tillerson said, however, that he hopes a way to oust Assad will “emerge” as part of de Mistura’s UN-mediated talks.‘Moment of truth’He argued that the UN Security Council resolution setting up the peace process already contains a procedure to hold elections that Washington does not think Assad can win.“The only thing that changed is when this administration came into office, we took a view that it is not a prerequisite that Assad go before that process starts, rather the mechanism by which Assad departs will likely emerge from that process,” he said.Earlier, de Mistura had told the UN Security Council that with the defeat of the Islamic State, the Syrian peace process had reached a “moment of truth.”“We need to get the parties into real negotiations,” the envoy said.Seven rounds of talks have achieved only incremental progress toward a political deal, with negotiations deadlocked over Assad’s fate.The opposition insists any settlement must provide for a transition away from Assad’s rule but, as government forces make gains, there is little likelihood of a breakthrough.
US president Donald Trump excuses reporters after his remarks to them at the start of a cabinet meeting at the White House in Washington, US, on 20 December 2017. ReutersUS president Donald Trump on Wednesday threatened to cut off financial aid to countries that vote in favor of a draft United Nations resolution calling for the United States to withdraw its decision to recognise Jerusalem as Israel’s capital.“They take hundreds of millions of dollars and even billions of dollars, and then they vote against us. Well, we’re watching those votes. Let them vote against us. We’ll save a lot. We don’t care,” Trump told reporters at the White House.The 193-member UN General Assembly will hold a rare emergency special session on Thursday – at the request of Arab and Muslim countries – to vote on a draft resolution, which was vetoed by the United States on Monday in the 15-member UN Security Council.The remaining 14 Security Council members voted in favor of the Egyptian-drafted resolution, which did not specifically mention the United States or Trump but which expressed “deep regret at recent decisions concerning the status of Jerusalem.”US Ambassador Nikki Haley, in a letter to dozens of UN states on Tuesday seen by Reuters, warned that Trump had asked her to “report back on those countries who voted against us.”She bluntly echoed that call in a Twitter post: “The US will be taking names.”Several senior diplomats said Haley’s warning was unlikely to change many votes in the General Assembly, where such direct, public threats are rare.Miroslav Lajcak, president of the General Assembly, declined to comment on Trump’s remarks, but added: “It’s the right and responsibility of member states to express their views.”A spokesman for UN Secretary-General Antonio Guterres also declined to comment on Trump’s remarks on Wednesday.“I like the message that Nikki sent yesterday at the United Nations, for all those nations that take our money and then they vote against us at the Security Council, or they vote against us potentially at the assembly,” Trump said.‘BULLYING’Trump abruptly reversed decades of US policy this month when he recognised Jerusalem as Israel’s capital, generating outrage from Palestinians and the Arab world and concern among Washington’s Western allies.He also plans to move the US embassy to Jerusalem from Tel Aviv. The draft UN resolution calls on all countries to refrain from establishing diplomatic missions in Jerusalem.A senior diplomat from a Muslim country, speaking on condition of anonymity, said of Haley’s letter: “States resort to such blatant bullying only when they know they do not have a moral or legal argument to convince others.”A senior Western diplomat, speaking on condition of anonymity, described it as “poor tactics” at the United Nations “but pretty good for Haley 2020 or Haley 2024,” referring to speculation that Haley might run for higher office.“She’s not going to win any votes in the General Assembly or the Security Council, but she is going to win some votes in the US population,” the Western diplomat said.A senior European diplomat, speaking on condition of anonymity, agreed Haley was unlikely to sway many UN states.“We are missing some leadership here from the US and this type of letter is definitely not helping to establish US leadership in the Middle East peace process,” the diplomat said.Israel considers Jerusalem its eternal and indivisible capital and wants all embassies based there. Palestinians want the capital of an independent Palestinian state to be in the city’s eastern sector, which Israel captured in a 1967 war and annexed in a move never recognised internationally.“The first name that she should write down is Bolivia,” Bolivia’s UN Ambassador Sacha Sergio Llorentty Solz said of Haley’s message. “We regret the arrogance and disrespect to the sovereign decision of member states and to multilateralism.”Read More: US warns countries over UN vote on Jerusalem
Suspended DIG Mizanur Rahman in the court. Photo: AsaduzzamanSuspended deputy inspector general (DIG) of police Mizanur Rahman was shown arrested in a case over bribing an official of the Anti-Corruption Commission (ACC), reports UNB.Dhaka senior special judge AKM Emrul Kayesh passed the order after accepting a petition filed by the ACC.On 16 July, ACC director Sheikh Mohammad Fanafillah submitted a petition for showing DIG Mizan arrested in the case.Lawyer Ehsanul Haque Samaji stood for DIG Mizan while Mosharraf Hossain Kajal and Tapash Kumar Pal represented the ACC and the state respectively.ACC director Sheikh Mohammad Fanafillah filed a case against suspended DIG Mizanur Rahman and ACC director Khandaker Enamul Basir with Dhaka-1 coordinated district office under the Anti-Corruption Commission, over Tk 4 million bribery scandal on 16 July.A private TV channel reported recently that Mizan gave Tk 4 million to Anti-Corruption Commission (ACC) director Khandaker Enamul Basir to get clean chit in a corruption case.DIG Mizan was an additional commissioner of Dhaka Metropolitan Police (DMP). He was withdrawn on 9 January last year following the allegation of threatening a female news presenter of a private television channel.He had also reportedly married a woman forcibly and tortured her. Mizan allegedly picked the 25-year-old woman up in July, 2017 and then forcibly married her.He had also implicated her in a false case whereby she was arrested and remained in jail for three weeks.The ACC on 24 June filed a case against four people, including DIG Mizanur Rahman, for amassing illegal wealth and concealing information.According to the case statement, the ACC found that DIG Mizan accumulated wealth worth Tk 32.8 million while he concealed information of wealth worth Tk 3.7 million in his wealth statement.
Andrew SchneiderPresident Trump has called NAFTA, the North American Free Trade Agreement, a “job killer” for American manufacturers. It’s a message voters in the industrial Midwest seemed to buy. But with the U.S. now renegotiating the treaty with Mexico and Canada, we found that manufacturers here in Texas are becoming deeply concerned.Daniel Allford is one of those manufacturers. We talked with him on the floor of his factory, ARC Specialties, on Houston’s west side. Allford started the company in his garage in 1983.“My whole life, all I’ve ever done is build things,” said Allford. “When I was a kid, I built catapults, flamethrowers, steam engines, and I’ve always been a computer geek. So if you add manufacturing and computers together, you get robotics.”ARC Specialties now employs more than 50 people to build robots, largely for the oil and gas industry. The company sold few machines to Mexico or Canada its first decade. Then NAFTA came along.“It was quite seamless to me. All I knew was all of a sudden exports became easy and greater quantity. It fluctuates, but last year 30 percent of our business was overseas, and half of that was Canada and Mexico,” said Allford.Allford said those gains came when NAFTA eliminated tariffs on his products, making them cheaper for foreign buyers. So when President Trump threatens to pull the U.S. out of NAFTA if Mexico and Canada don’t agree to revisions, he’s aiming right at Allford’s bottom line. “So far, I can’t say that it’s affected me,” said Allford, “but I’m sure it will if tariffs are placed.”Allford is hardly alone in his fears. Jeff Moseley is CEO of the Texas Association of Business. He recently testified before a Senate subcommittee hearing on NAFTA in San Antonio.“Since 2006, Texas exports of goods to NAFTA signatories have grown 71 percent,” said Moseley. “An undermining of the tariff policies that have allowed that growth would have huge detrimental effects in most sectors of the Texas economy.”Governor Greg Abbott and Senator John Cornyn have made that point to President Trump often. But the message doesn’t seem to be having much effect. Stephen P. Vaughn, general counsel in the Office of the U.S. Trade Representative, testified at the same hearing.“Of course, there are Americans who benefit from NAFTA, and we want to avoid harming them,” said Vaughn. “But USTR must look at trade deals from the perspective of the country as a whole, and from that perspective, there are serious problems with NAFTA.” Vaughn said that over the past decade, the U.S. racked up a $500 billion trade deficit with Mexico and a $100 billion deficit with Canada.George Y. Gonzalez, a partner at the law firm of Haynes and Boone, said that may be true, but it misses the point.“Regional trade was at $290 billion in 1993 among the three countries. In 2016, it’s at $1.1 trillion,” said Gonzalez, arguing that jump in North American trade created more jobs than it cost. “It’s the very opposite of what the rhetoric is, in fact. The implementation of NAFTA has preserved jobs and has maintained a vibrant and competitive U.S. manufacturing position.”Daniel Allford at ARC Specialties said he doesn’t have to imagine what will happen to his sales if the U.S leaves NAFTA. “In the countries that NAFTA doesn’t cover – for example, in Brazil, there’s 40 percent tariffs on my equipment,” he said. “What this means is I have yet to sell a machine to a Brazilian company.”President Trump has set a deadline of March to wrap up the NAFTA talks. Any longer, and they risk bumping up against the Mexican presidential election and campaigning for the U.S. congressional midterms. X To embed this piece of audio in your site, please use this code: 00:00 /03:59 Listen Share
A Centennial Legend’s Scholarship Gala will be held 7 p.m., June 13 in Dr. Hooker’s honor in the metropolitan area at Marriot Wardman Park, 2660 Woodley Rd NW. Tickets cost $20. This year the goal is to raise $10,000 to $20,000 to provide scholarships for college bound students or students currently enrolled in college under the Dr. Olivia J. Hooker Scholarship Fund. This event would feature universally recognizable women that have made great strides in their distinguished careers and Dr. Olivia Hooker’s Scholarship recipients. The women’s and students’ achievements will be highlighted with brief presentations or a short film as a part of their introduction. For more information, contact LCDR Rhonda Fleming-Makell (Retired) at (301) 266-5050 or email@example.com.
Facebook wants to launch a dedicated tab within its app to aggregate content from news publishers, CEO Mark Zuckerberg revealed during a conversation with Springer CEO Mathias Doepfner Monday morning. Plans for the news section are still in early stages, according to Zuckerberg, who said that the company was looking for input from the news industry. “We don’t want to build this in a vacuum,” he said.Zuckerberg likened the planned news tab to the way the company has broken out video in its Watch tab, which is aggregating video from a number of publishers, some of which are producing video exclusively for the platform. Facebook Watch “has started to really grow quickly,” Zuckerberg said. “We’ve decided that there really is an opportunity to do something like this with news as well.” Facebook Reportedly Working on New Snapchat-Like Messaging App for Instagram Former Oculus Head of Mobile VR Max Cohen Leaves Facebook Popular on Variety Zuckerberg didn’t share many additional details, and said the company was still trying to figure out how to balance curation with aggregation of the sources a user was already following. He also suggested that the company was looking to give publishers new ways to make money. “There is a real opportunity to have better monetization for publishers than we have today at news feed,” he said. Related He cited Facebook’s news subscription efforts as evidence that the company was looking to support the industry financially, but also had to admit that these efforts haven’t been very impactful yet. “That’s off to a reasonable start. There is lots more to do there,” he said.Facebook’s commitment to double down on news comes after the company began to de-emphasize news articles in its main news feed to re-focus on personal connections between its users. Those changes, instituted in early 2018, resulted in a 20% drop of news content shown to its users, according to numbers shared by Facebook executives shared at the time.Facebook posted a video of Zuckerberg’s hourlong conversation with Doepfner Monday morning as a first of what is supposed to be a series of talks about the future of the internet and society. Doepfner was a bit of a polarizing choice to kick off the series: The Springer CEO has led the company’s foray into the digital space, but has also been a strong advocate of recent European copyright changes, commonly known as “Article 13,” that have been criticized by many as being harmful to the internet.In his conversation with Zuckerberg, Doefner celebrated the European parliament’s recent passage of those changes, likening them to the compulsory licensing regimen the music industry has been working with for decades, and suggesting Facebook should adhere to similar rules.Article 13 had gotten a lot of public push-back from Google in particular, with YouTube CEO Susan Wojcicki arguing that it would make it impossible for millions of users to upload content to her site, or to view content posted by U.S. creators.But on Monday, Zuckerberg seemed open to embrace similar rules. “That’s definitely something we should be thinking about here,” he said with regards to Article 13, while also cautioning that “there is a lot of details to be worked out there.” ×Actors Reveal Their Favorite Disney PrincessesSeveral actors, like Daisy Ridley, Awkwafina, Jeff Goldblum and Gina Rodriguez, reveal their favorite Disney princesses. Rapunzel, Mulan, Ariel,Tiana, Sleeping Beauty and Jasmine all got some love from the Disney stars.More VideosVolume 0%Press shift question mark to access a list of keyboard shortcutsKeyboard Shortcutsplay/pauseincrease volumedecrease volumeseek forwardsseek backwardstoggle captionstoggle fullscreenmute/unmuteseek to %SPACE↑↓→←cfm0-9Next UpJennifer Lopez Shares How She Became a Mogul04:350.5x1x1.25×1.5x2xLive00:0002:1502:15
Physicists performed a Bell experiment between the islands of La Palma and Tenerife at an altitude of 2,400 m. Starting with an entangled pair of photons, one photon was sent 6 km away to Alice, and the other photon was sent 144 km away to Bob. The physicists took several steps to simultaneously close the locality loophole and freedom-of-choice loophole. Image credit: Thomas Scheidl, et al. and Google Earth, ©2008 Google, Map Data ©Tele Atlas. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. (PhysOrg.com) — The latest test in quantum mechanics provides even stronger support than before for the view that nature violates local realism and is thus in contradiction with a classical worldview. By performing an experiment in which photons were sent from one Canary Island to another, physicists have shown that two of three loopholes can be closed simultaneously in a test that violates Bell’s inequality (and therefore local realism) by more than 16 standard deviations. Performing a Bell test that closes all three loopholes still remains a challenge, but the physicists predict that such an experiment might be “on the verge of being possible” with state-of-the-art technology. More information: Thomas Scheidl, et al. “Violation of local realism with freedom of choice.” 19708-19713, PNAS, November 16, 2010, vol. 107, no. 46. DOI:10.1073/pnas.1002780107 The physicists, who belong to the group of Rupert Ursin and Anton Zeilinger and were all at either the Austrian Academy of Sciences in Vienna or the University of Vienna when performing the experiments in 2008, have published their study on the new Bell test in the early edition of PNAS. As they explain in their study, local realism consists of both realism – the view that reality exists with definite properties even when not being observed – and locality – the view that an object can only be influenced by its immediate surroundings. If a Bell test shows that a measurement of one object can influence the state of a second, distant object, then local realism has been violated.”The question of whether nature can be understood in terms of classical concepts and explained by local realism is one of the deepest in physics,” coauthor Johannes Kofler told PhysOrg.com. “Getting Bell tests as loophole-free as possible and confirming quantum mechanics is therefore an extremely important task. From a technological perspective, certain protocols of quantum cryptography (which is entering the market at the moment) are based on entanglement and violation of Bell’s inequality. This so-called ‘unconditional security’ must in practice take care of the loopholes in Bell tests.”The physicists explained that, in experimental tests, there are three loopholes that allow observed violations of local realism to still be explained by local realistic theories. These three loopholes can involve locality (if there is not a large enough distance separating the two objects at the time of measurement), the freedom to choose any measurement settings (so measurement settings may be influenced by hidden variables, or vice versa), and fair sampling (a small fraction of observed objects may not accurately represent all objects due to detection inefficiencies).Previous experiments have closed the first loophole, which was done by ensuring a large spatial separation between the two objects (in this case, two quantum mechanically entangled photons) so that measurements of the objects could not be influenced by each other. Special relativity then ensures that the objects cannot influence each other, since no physical signals can travel faster than the speed of light. In these experiments, classically unexplainable correlations were still observed between the objects, indicating a violation of local realism. (The fair sampling loophole was closed in another earlier experiment using ions, where large detection efficiencies can be reached.) Debunking and closing quantum entanglement ‘loopholes’ Citation: Physicists close two loopholes while violating local realism (2010, November 30) retrieved 18 August 2019 from https://phys.org/news/2010-11-physicists-loopholes-violating-local-realism.html Explore further In the current experiment, the physicists simultaneously ruled out both the locality loophole and the freedom-of-choice loophole. They performed a Bell test between the Canary Islands of La Palma and Tenerife, located 144 km apart. On La Palma, they generated pairs of entangled photons using a laser diode. Then they locally delayed one photon in a 6-km-long optical fiber (29.6-microsecond traveling time) and sent it to one measurement station (Alice), and sent the other photon 144 km away (479-microsecond traveling time) through open space to the other measurement station (Bob) on Tenerife. The scientists took several steps to close both loopholes. For ruling out the possibility of local influence, they added a delay in the optical fiber to Alice to ensure that the measurement events there were space-like separated from those on Tenerife such that no physical signal could be interchanged. Also, the measurement settings were randomly determined by quantum random number generators. To close the freedom-of-choice loophole, the scientists spatially separated the setting choice and the photon emission, which ensured that the setting choice and photon emission occurred at distant locations and nearly simultaneously (within 0.5 microseconds of each other). The scientists also added a delay to Bob’s random setting choice. These combined measures eliminated the possibility of the setting choice or photon emission events influencing each other. But again, despite these measures, the scientists still detected correlations between the separated photons that can only be explained by quantum mechanics, violating local realism.By showing that local realism can be violated even when the locality and freedom-of-choice loopholes are closed, the experiment greatly reduces the number of “hidden variable theories” that might explain the correlations while obeying local realism. Further, these theories appear to be beyond the possibility of experimental testing, since they propose such things as allowing actions into the past or assuming a common cause for all events. Now, one of the greatest challenges in quantum mechanics is simultaneously closing the fair-sampling loophole along with the others to demonstrate a completely loophole-free Bell test. Such an experiment will require very high-efficiency detectors and other high-quality components, along with the ability to achieve extremely high transmission. Also, the test would have to operate at a critical distance between Alice and Bob that is not too large, to minimize photon loss, and not too small, to ensure sufficient separation. Although these requirements are beyond the current experimental set-up due to high loss between the islands, the scientists predict that these requirements may be met in the near future. “Performing a loophole-free Bell test is certainly one of the biggest open experimental challenges in the foundations of quantum mechanics,” Kofler said. “Various groups are working towards that goal. It is on the edge of being technologically feasible. Such an experiment will probably be done within the next five years.” Copyright 2010 PhysOrg.com. All rights reserved. This material may not be published, broadcast, rewritten or redistributed in whole or part without the express written permission of PhysOrg.com.
Naked Molerat Heterocephalus glaber eating. Image: Wikipedia. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Explore further Perhaps even more interesting is the fact that because they live so close together underground, carbon dioxide builds up in their den to levels that would kill most other mammals, and because oxygen levels are low too, an environment exists that would prove painful for most animals due to acid buildup in tissues. Mole rats are impervious to pain from acid though, a fact that has intrigued scientists for years. Most assumed they simply had different types of nociceptors than other mammals. But that’s not the case, as Gary Lewin and his colleagues from the Max Delbrück Center for Molecular Medicine in Berlin write in their paper published in Science. Instead, it appears the mole rats have a species specific variant of a certain sodium channel.In order to feel things such as acid burn, animals have sensory neurons in their tissues, the tips of which have channels called nociceptors which control the flow of sensory information to the neuron, which is responsible for sending electrical signals to the brain. Channels can let things through, or slam shut blocking things off depending on the cause of the stimulation. In the case of acid, nociceptors for most mammals are stimulated and partially close, but let enough of the sensory information pass through to allow the brain to feel the pain acidic substances create. Oddly enough, the team found that to be the case with mole rats too, which meant they had to look elsewhere. In this case that meant looking at another type of sodium channel, called NaV1.7, which they found became blocked when exposed to acid.This new discovery by the team means they have discovered that an animal doesn’t have to have a unique type of nociceptor in order to be free from acid pain, all that’s necessary is a change in the NaV1.7 channel that directs the flow of information passed on to neuron below. This is quite a find because it could lead to ways to alleviate certain kinds of pain that people experience, such as inflammation from arthritis. Journal information: Science More information: The Molecular Basis of Acid Insensitivity in the African Naked Mole-Rat, Science, 16 December 2011: Vol. 334 no. 6062 pp. 1557-1560. DOI: 10.1126/science.1213760ABSTRACTAcid evokes pain by exciting nociceptors; the acid sensors are proton-gated ion channels that depolarize neurons. The naked mole-rat (Heterocephalus glaber) is exceptional in its acid insensitivity, but acid sensors (acid-sensing ion channels and the transient receptor potential vanilloid-1 ion channel) in naked mole-rat nociceptors are similar to those in other vertebrates. Acid inhibition of voltage-gated sodium currents is more profound in naked mole-rat nociceptors than in mouse nociceptors, however, which effectively prevents acid-induced action potential initiation. We describe a species-specific variant of the nociceptor sodium channel NaV1.7, which is potently blocked by protons and can account for acid insensitivity in this species. Thus, evolutionary pressure has selected for an NaV1.7 gene variant that tips the balance from proton-induced excitation to inhibition of action potential initiation to abolish acid nociception. Study: Why cold is such a pain © 2011 PhysOrg.com (PhysOrg.com) — Mole rats aren’t the prettiest things; living underground as they do, they more resemble Gollum from the Lord of the Rings trilogy than other rats or mice. But they’re interesting to scientists nonetheless because they have some interesting traits. They live for twenty years for example, and none of them ever get cancer. Citation: Researchers uncover reason why mole rats are oblivious to acid pain (2011, December 16) retrieved 18 August 2019 from https://phys.org/news/2011-12-uncover-mole-rats-oblivious-acid.html
Kolkata: The Criminal Investigation Department (CID) of the state has taken over investigation of the Kajipara blast case. On Wednesday, all the documents and evidences have been handed over to CID by the Barrackpore Police.Immediately after the investigation was handed over, a CID team led by Deputy Inspector General (DIG) Pranav Kumar visited the spot in the afternoon. Apart from CID, a team from the Central Forensic Science Laboratory (CFSL) also visited the spot. Also Read – Rain batters Kolkata, cripples normal lifeSources informed that as per direction from Chief Minister Mamata Banerjee, CID took over investigation of the case. On Wednesday afternoon, investigators visited the flats in the building in front of which the blast took place on Tuesday. The owners and residents of the flats were also questioned.Later, CID officials measured the distance of damaged points from the blast spot. The shutter opposite the blast spot, which was also damaged, was opened. After opening the shutter it was found that a splinter had penetrated the shutter and damaged a showcase inside. Also Read – Speeding Jaguar crashes into Mercedes car in Kolkata, 2 pedestrians killedCID officials also looked for Close Circuit Television (CCTV) cameras present in the locality, to find out what actually happened. As no CCTV camera was available, sleuths turned towards the conventional method of enquiry by questioning the locals. According to CID sources, it is being suspected that the bomb which exploded on Tuesday was bigger than average socket bombs. Ammonium nitrate and acid were also used to intensify the blast. The cap at the bottom of the bomb was tighter than the upper one. As a result, most of the explosion was directed upwards, which cracked the windows inside the blast radius. Experts have collected samples and sent them for necessary examination.
August 29, 2016 Free Workshop | August 28: Get Better Engagement and Build Trust With Customers Now U.S. businesses can now legally operate drones.A new rule goes into effect today that allows people to operate small unmanned aircraft systems (UAS) for commercial purposes. It takes the form of the “Part 107” amendment to the Code of Federal Regulations Title 14, which consists of laws regarding aeronautics, aviation and space exploration. The FAA and the Department of Transportation have jointly prepared a 624-page document outlining the various stipulations.Related: NoFlyZone Wants to Help Keep Drones From Flying Over Your HomeThe UAS must:Weigh less than 55 pounds.Remain within the visual line of site of the remote pilot in command and the person manipulating the flight controls. (Alternatively, the UAS must remain within the visual line of sight of a second individual, a designated but unrequired “visual observer” who is not piloting it. Only one remote pilot in command and one visual observer is allowed per UAS.)Remain close enough to the pilot and the person manipulating the flight controls for those people to see the aircraft with unaided vision (with the exception of corrective lenses).Not operate over any persons not directly participating in the operation.Not operate under a covered structure.Not operate inside a covered stationary vehicle.Operate only during daylight or “civil twilight” (30 minutes before official sunrise to 30 minutes after official sunset, local time) with appropriate anti-collision lighting.Must yield right of way to other aircraft.Not exceed a maximum ground speed of 100 mph (87 knots).Not exceed a maximum altitude of 400 feet above ground level unless within 400 feet of a structure.Operate in a minimum weather visibility of three miles from control station.Not operate from a moving aircraft.Not operate from a moving vehicle unless the operation is over a sparsely populated area.Not carry hazardous materials.Undergo preflight inspection by the remote pilot in command.Not be operated by a person who knows or has a reason to know that he or she has a physical or mental condition that would interfere with safe operation.Other info:Foreign-registered small UAS are allowed to operate under Part 107 if they satisfy other requirements.The flight must occur wholly within the bounds of a state and may not involve transport between Hawaii and another place in Hawaii through airspace outside Hawaii; the District of Columbia and another place in the District of Columbia; or a territory or possession of the United States and another place in the same territory or possession.Most of the restrictions discussed above are waivable if the applicant demonstrates that his or her operation can safely be conducted under the terms of a certificate of waiver.Those piloting small UAS must meet a list of requirements as well, from remote pilot airman certification (with a small UAS rating) to vetting by the TSA. In addition, all UAS must be registered with the FAA.Previously, commercial drone operation was illegal unless a business qualified for an exemption, which was a lengthy and expensive process.Goldman Sachs industry research predicts that the global commercial drone market is expected to grow to $20.6 billion over the next five years, according to MarketWatch. Cell tower and wind turbine maintenance, roof inspections and surveying are some of the fields that will benefit greatly today’s changes.Related: Heads Up: Amazon Wants Delivery Drones to Find You Wherever You AreDrone groups have commended the government for finalizing the rule so quickly. In February 2015, the Government Accountability Office estimated a two- to three-year wait, according to Aviation Daily. A year and a half later, the FAA has delivered on getting it through “as expeditiously as possible.”While Amazon drone deliveries are still illegal given the limitations of the new rule, the government’s seemingly positive attitude toward commercial drone operations shows promise for future developments. This hands-on workshop will give you the tools to authentically connect with an increasingly skeptical online audience. 4 min read Enroll Now for Free
<< Previous PostNext Post >> TORONTO — A recent independent survey of Canadian home-based travel agents found that over 50% of them had made the decision to go home based in the last five years, explaining the astonishing growth in this sector all of a sudden. It is now thought that about 33% of all Canadian travel agents work from home.Over 60% of the home based agents surveyed were experienced agents working in a bricks and mortar agency before choosing to go home based. This dispels the false idea that home based agents are new to the industry and inexperienced. On the contrary, most home based agents have over 20 years’ experience in the industry.And almost half said they were earning more now than when they worked in a bricks and mortar agency.But the main reason these experienced agents are giving up their office positions seems to be about wanting to be their own boss. That and improving their work/life balance, as we have stated in an earlier article.Experienced agents also have usually gathered a good book of business as well, and have loyal clients who will follow them.The survey of almost 200 hosted travel agents across Canada included agents from all the leading host agencies. It was commissioned in December 2016 by The Travel Agent Next Door to gain further insight into the growing number of hosted agents and to determine how best to serve their needs in the future.The agents surveyed were currently affiliated with eight different host agencies from across Canada, with 12% not divulging who they were associated with.Flemming Friisdahl, Founder of The Travel Agent Next Door, says his company will continue to invest in third party research into the home based sector and he fully intends to share this information with the industry. “By understanding home based agents better, we can offer the best programs for their needs,” said Friisdahl. Tags: Sphere, The Travel Agent Next Door By: Jill Wykes, The Travel Agent Next Door Phenomenal growth in home based agent sector is recent, survey shows Wednesday, March 15, 2017 Share About Latest Posts Jill WykesJill Wykes is a travel industry veteran who has held a series of senior management portfolios in travel corporations. A former chairman of the Travel Industry Council of Ontario, she is now an independent communications consultant and writer since retiring in 2011. Latest posts by Jill Wykes (see all) Dispelling the myths against going home-based – May 22, 2019 Diversity pays off when agents go home-based: Survey – April 10, 2019 National Travel Agent survey suggests many agents considering going home-based – March 13, 2019
October 29, 2016Film director Aimee Madsen and Cosanti Foundation Directors Mary Hoadley and Roger Tomalty are in New Mexico to screen PAOLO SOLERI – BEYOND FORM, last night in Albuquerque. [photos by Aimee Madsen]Aimee:We screened to a sold out audience in Albuquerque. So grateful to every one who made it possible. Next comes Santa Fe on the 29th!see: http://www.architecturesantafe.org/film-series.html
09Jan Rep. Joe Bellino, R-Monroe; audio on pension tax repeal – 0:00:00 / 0:00:00Update RequiredTo play the media you will need to either update your browser to a recent version or update your Flash plugin. playpause playpause playpause Categories: Audio,Bellino Audio,News – 0:00:00 / 0:00:00Update RequiredTo play the media you will need to either update your browser to a recent version or update your Flash plugin. – 0:00:00 / 0:00:00Update RequiredTo play the media you will need to either update your browser to a recent version or update your Flash plugin. Rep. Bellino talks about his legislation, introduced on the first day of the 2019-2020 session of the Legislature, that would repeal the state’s pension tax. Rep. Bellino says Michigan’s economy has improved significantly since the tax was enacted in the early part of the decade.
In “Future Foods: How Modern Science Is Transforming the Way We Eat” (Springer Nature, 2019), McClements poses and explores an array of science-meets-food questions, such as: What is food architecture? It’s the use of architectural and design principles to construct healthier, tastier and more sustainable foods. Will we all one day have 3-D food printers in our homes? Yes, and they are already available. Should nanotechnology and gene editing be used to enhance our foods? It’s a very complicated area, but McClements concludes we need to harness new technology to feed the world and sustain the planet. What’s the best way to customize your diet for better health? Hint: one size does not fit all.The book discusses efforts to create functional foods, which are fortified with nutraceuticals or probiotics to address malnutrition in developing countries and combat chronic disease, such as cancer, diabetes and obesity. While he stresses the need for consuming more fruits, vegetables and other fresh foods, McClements points out that this is not “practical” for everybody on Earth, not to mention in space. McClements and fellow food scientists at UMass Amherst are working with NASA to design functional foods for astronauts on a would-be mission to Mars. Related StoriesRaw meat can act as reservoir for bacteria associated with hospital infectionsComplement system shown to remove dead cells in retinitis pigmentosa, contradicting previous researchTrump administration cracks down on fetal tissue researchThe book’s tone is conversational and lively, and McClements shares personal anecdotes of his and his family’s explorations with new foods. In Scotland, his nephew Jake conducted an informal taste-test of a bag of crunchy edible insects, illustrated with a photograph of him about to rip into a slice of pizza topped with barbecue-flavored crickets. In South Beach, McClements is seen biting into his first plant-based Impossible Burger and reflecting on its meat-like appearance, flavor and mouthfeel.A vegetarian for the past few years, McClements emphasizes the importance of creating a “more ethical and sustainable edible future” and provides historical context about the world’s food consumption, production and needs.Meat-alternative products like the Impossible Burger are becoming more available and even delicious, and McClements explains that “clean meat” and “bug meat” are not far behind. Clean meat, also called cultured meat, is created from the living cells of animals that are grown in test tubes or fermentation vats (like beer), using advanced biomedical technology. “You actually get meat,” McClements says, “without any animal being killed.”In “Future Foods,” McClements originally set out to answer a personal question and a global quandary: “What should my family and I eat? How should we feed the growing world population?” In the end, McClements discovered that the meat of the book “was really about complexity, uncertainty, and compromise.”He writes in the final chapter, “My journey through the future of foods has been both an enlightening and humbling experience.” There are so many exciting things going on in the food science area. We’re in the midst of an unprecedented era of rapid scientific and technological advances that are transforming the way our foods are produced and consumed.”David Julian McClements Source:University of Massachusetts at Amherst What we really need are processed foods that are affordable and convenient but also healthy and tasty.”David Julian McClements Reviewed by James Ives, M.Psych. (Editor)May 27 2019David Julian McClements, Distinguished Professor of Food Science at the University of Massachusetts Amherst and among the world’s most highly cited researchers, has written a new book that explores the brave new world of science and food.For the first time, the acclaimed researcher and academic author has geared a book about food science toward a general audience, encouraged by his teenage daughter, who did research in his lab on plant-based foods as a high school student and is heading to Vassar College in the fall.
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Here are some sayings the company uses to describe the product; “any wine any amount, savor the glass preserve the bottle, just insert tip and pour” and my favorite “The wine you want in the amount you want without ever pulling the cork.”But “Open a bottle,” which is scribbled out, is the line you need to know because the bottle doesn’t open. Call it magic, or just call it technology as I would prefer. Either way, this is an incredibly innovative device, which works to perfection.How does it work? At last month’s Consumer Electronics Show in Las Vegas, Coravin displayed the upcoming model 11, which should set you back around $999. It shoots a thin needle into the bottle’s cork and any wrapping the cork is sealed in. No need to remove anything.A thin needle was inserted into the bottle, and then a company representative kindly poured me a glass of wine (I was not driving this night). She handed me the bottle to inspect, and it was a real bottle, no hidden curtains, no rabbit in a box, just a wine opener and a bottle. Which I then turned over to see if anything would spill and it was dry, not a drop. Upon close inspection of where the needle entered, you can barely see any evidence.This system allows your wine to remain fresh since the cork is not removed. My demonstrator explained after the Coravin is removed, the cork simply shrinks back together.The Coravin holds your bottle, and with load cell technology, the capsule-loading chamber creates the perfect amount of force for an airtight seal, ensuring no gas escapes after probing the bottle. According to Coravin, the capsules contain more than 99.99 percent pure argon gas to protect the remaining wine from oxidation.If the high-end price model scares you, there are more choices. The Coravin Model Two Wine System gives wine lovers the freedom to pour any wine, in any amount, without removing the cork for a sip or full glass.Model Two its referred to as an elegant design and durable craftsmanship with textured rubber grips and ergonomic lines. It includes two Coravin capsules to pour up to 30 glasses of wine. Model 11 will be out in September and will have an app to make it the world’s first connected and fully automatic wine preservation opener. The app will make suggestions for wine and will show how much gas is left in the capsules. Scientists to settle dispute over taste of wine in bottles with corks versus screw caps Explore further ©2018 Gregg Ellman Distributed by Tribune Content Agency, LLC. Citation: Gadgets: Device lets you pour the wine without removing the cork (2018, January 31) retrieved 18 July 2019 from https://phys.org/news/2018-01-gadgets-device-wine-cork.html www.coravin.com —-For $39.97 the Bluetooth (4.2) sound you get from a pair of Kempler and Strauss X2 wireless speakers is great for many reasons.While these are ideal for travel, why not use them on your desk at home or just about anywhere. They’re small, cool, have great sound and even live on a magnetic charging base, which is great when you see them snap in place.Each charge is good for about 4 hours with the internal 450mAh rechargeable batteries in each speaker.The speakers come in a pair so they can be separated for a wireless stereo sound.Think of them as donut holes, and you’ll understand the size of 1.9-by-1.2-inches each with a 2.4-ounce weight all packed into an aluminum body. And if you don’t eat donut holes, you haven’t lived.Travel straps to attach to each speaker are included along with a charging cable and a USB AC adapter plug. www.kemplerusa.com $39.97 in black or silver When you hear about the Coravin wine bottle opener, you might think it’s just another gimmicky gadget. I think it’s something you must see to believe. A few weeks ago, I saw it, I believed it, and I even had a drink out of it to prove it.
A startup is using Purdue University-patented technology to produce precise, customized medicine for pets. Arun Giridhar is one of the co-founders of Pinpoint Pharma, a precision compounding pharmacy for veterinarians. Pinpoint Pharma has created a printer that is faster than traditional methods of making customized medicine that is tailored to each individual animal’s needs. Credit: Purdue Research Foundation image/Oren Darling Provided by Purdue University Pinpoint Pharma has created a device similar to an inkjet printer that can precisely dispense pharmaceuticals to meet a growing need for customized medication for pets. Credit: Purdue Research Foundation image/Oren Darling While it can take more than an hour to produce a batch of 100 to 300 capsules, Pinpoint Pharma’s printer cuts the total time per patient to 10 minutes, including cleanup, and is flexible on the product form suited to the individual pet.”We can make about one dose every second, or even faster,” Giridhar said. The printer also is more precise, using a tracking mechanism to record how many drops of medicine are dispensed in each dose and the volume of each drop, in real time. Typically making a batch of pills can have variances in potency between doses, Giridhar said.The printer also helps make potent medications that have a narrow therapeutic index, where small differences in dose concentration can lead to serious therapeutic failures or adverse drug reactions.”In such cases, it becomes important to dose very precisely,” Giridhar said.Giridhar said what sets Pinpoint Pharma apart is that the team has more experience in this field and the company has worked with a wide variety of medications.Earlier this year, the startup was chosen by gener8tor, a nationally ranked accelerator based in Milwaukee, for its gBETA program, a seven-week accelerator for early-stage companies with local roots. Pinpoint Pharma was one of five startups selected from 52 applicants for the inaugural Indiana cohort; gener8tor also operates programs in Wisconsin, Michigan, Ohio and Minnesota. The program provides mentors, advice on business models and suggestions on ways to grow. It also gives the startups office space and up to $1 million in deals and perks from vendors.”Our experience with gBETA has helped Pinpoint Pharma move forward with our business model and develop new relationships with customers, mentors and investors,” Giridhar said. Explore further This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Researchers commercialize drug dosage printer to improve personalized medicine production, cut side effects Pinpoint Pharma has created a printer that is faster than traditional methods of making customized medicine. The company is among three startups receiving assistance from the Purdue Foundry and eight startups from Indiana that will be featured Sept. 5-7 at the TechCrunch Disrupt SF Conference in San Francisco.Pinpoint Pharma is a precision compounding pharmacy for veterinarians, ensuring that the medicine tailored to each individual animal’s needs is easier for pet owners to give and for pets to take, which optimizes clinical outcomes.Arun Giridhar, Pinpoint Pharma’s chief executive officer, and three faculty members of Purdue’s Department of Industrial and Physical Pharmacy and Davidson School of Chemical Engineering founded Pinpoint Pharma two years ago, and have been joined recently by Angela Demaree, a nationally known veterinarian, who received her DVM from Purdue. The goal was to create a device like an inkjet printer that could precisely dispense pharmaceuticals to meet a growing need for customized medication for pets instead of a one-size-fits-all approach generally taken.”When a pet has a specific requirement as determined by their vet, we can dispense the exact amounts and ratios of active ingredients needed for a pill, in a form and flavor that the specific pet will love,” Giridhar said.For pets, the one-size-fits-all method doesn’t always work.”Our medicine printer allows veterinarians to be very precise in serving an animal as an individual rather than as the average of a population.”Giridhar said Pinpoint Pharma’s medicine printer has two advantages over other methods used to make customized drug products: it is faster and more precise. Citation: Startup creates printer that makes customized medicines for pets (2018, September 5) retrieved 17 July 2019 from https://phys.org/news/2018-09-startup-printer-customized-medicines-pets.html
Prime Minister Narendra Modi – Reuters national politics COMMENTS About 63 per cent of respondents participated in a digital survey conducted by a content aggregator and a market research agency have said they have more or similar levels of trust in Prime Minister Narendra Modi’s abilities to steer the country as compared to 2014 and half the participants felt a second term for him would be good for them.The survey was carried out by Daily Hunt and Nielsen India and they claimed that 5.4 million people who are frequent visitors to the former’s platforms in 10 different languages participated in the survey. The results of the survey conducted during last month were announced here on Thursday.Revealing the findings, Daily Hunt President Umang Bedi said the survey was not politically-motivated. “Our only motivation was to bring out the voice of real Bharat,” Bedi said adding that a large number of respondents were from tier 2 and tier 3 towns and cities. According to the survey, 60 per cent of the respondents felt Modi was a better leader to root out corruption followed by Arvind Kejriwal (15 per cent) and Rahul Gandhi (14 per cent). About 62 per cent of the participants said Modi was their pick for leading the nation during a national crisis. Rahul Gandhi came a poor second with 17 per cent rooting for him.Interestingly, most south Indian States, barring Karnataka, were circumspect about Modi’s leadership qualities, while half or more respondents from the States in other geographic regions gave him a thumbs-up, the firms claimed. COMMENT Published on November 01, 2018 SHARE SHARE SHARE EMAIL Respondents from most southern States barring Karnataka were however circumspect about PM’s leadership qualities